99% Effective Muscle Growth Steroids Sarm Raw Powder Sr9011 1379686-29-9

Product Description

SR9011
CAS:1379686-30-2
Molecular formular:C20H24ClN3O4S
Molecular Weight:437.94
Appearance: White powder

Description:

SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.

The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia.

These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.

How to Use SR9011?

In vitro: SR9011 was used at 5-10 uM concentration in vitro and in cellular assays.
In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.

SR9011 Powder Usage:

A new compound called SR9011 increases metabolism, fat burning, and muscle growth in the lab.Scientists at The Scripps Research Institute (TSRI) have successfully tested a drug, called SR9011,in mice that kickstarts metabolism and results in increased muscle development.Essentially, it's an exercise regime in a pill.

SR9011 alters the metabolic profile of skeletal muscle in a manner similar to the changes observed in animals that are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify its metabolism.

Half of the mice studied showed improved running endurance in terms of both time and distance. What was clearly interesting was that a small, drug-like molecule could increase metabolic rate in skeletal muscle and increase exercise endurance.

1.AICAR: acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown.

2.MK-2866: Medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testosterone Replacement Therapy.
 
4.LGD-4033: Pharmacological profile similar to that of enobosarm, Ostarine,MK-2866.

5.GW1516: For obesity, diabetes, dyslipidemia and cardiovascular disease.

6.Andarine(S4): Partial agonist, intended mainly for treatment of benign prostatic hypertrophy.

7.SR9009: Under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice.

8.SR9011: For obesity, diabetes, dyslipidemia and cardiovascular disease.

9.RAD140: New generation for gaining mass and cutting edges.

10.YK11A: SARM and myostatin inhibitor.

Related Products  

How to order quickly and safely? 

    

 
Packaging









Shipping Method










Company Information
Hubei Shinrezing Pharmaceutical Technology Co.,Ltd.(hereafter shorted as Shinrezing) is located in Wuhan Donghu High-Tech Economic Development Zone and established in 2008 with registered capital is RMB 10 million yuan (about USD 1.5 million ). Its manufacturing base is located in Dawu Industrial Park in Dawu County, Xiaogan City, Hubei Province which is built in 2010 with 25,000 square meters covered area.
 
Shinrezing is a rapid growing enterprise, which integrates the production, R&D, sales and trading of APIs, steroid raw materials, pharmaceutical intermediates, plant extracts, other kinds of organic intermediates etc. Shinrezing is not only a manufacturing company but also a trade company, it also has very good cooperation relationships with some manufacturers qualified with GMP, DMF to meet the different customers' needs from grams to tonnage quantity, which makes Shinrezing to be more flexible and easily to supply highly cost-effective products with high quality and better service to customers.
Shinrezing always stands in high starting, high stand and high quality, and masters strict management for production procedure and quality control. All the products must pass our quality test before being sending to customers. Shinrezing's products have been exported to more than 50 countries and regions all over the world, including United States, Europe, Japan, Korea, Russia, Hong kong, Taiwan and so on, and enjoy a good reputation from domestic and oversea customers
 
Shinrezing's mission is: "Innovative and Pragmatic, Mutual Benefits, Serve the World". Every staff member will keep this in mind all the time, and enforce it at every detail of operation and management of the company. We are always trying our best to offer the best services and the most competitive prices with high quality goods for our customers. All honors belong to the past, Shinrezing people will do their best to develop and produce more perfect product and contribute to the chemical pharmaceutical industries worldwide.

We are confident that Shinrezing will be your best solution.





 
FAQ
Order Guide
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept bank transfer, Western Union or Paypal or  Moneygram

Q6:How long does it take to the goods arrived ?
It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7  Do  you  have  any  reshipment  policy ?  
we have good after-sale service and re-shipment policy if the parcel  lose
Our long association with  our clients has brought great benefits
We always take the upmost care in the packaging of our products 
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible  will seize a small number of packages.
In this circumstance we promise reship free  to establish  long term relationship
 
Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.
 
We have formed a technology and management team that cooperate closely with some  overseas Labs  all speak highly of our safe shipping and goods .
please donot hesitate to contact us.
 

Product Description

SR9011
CAS:1379686-30-2
Molecular formular:C20H24ClN3O4S
Molecular Weight:437.94
Appearance: White powder

Description:

SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.

The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia.

These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.

How to Use SR9011?

In vitro: SR9011 was used at 5-10 uM concentration in vitro and in cellular assays.
In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.

SR9011 Powder Usage:

A new compound called SR9011 increases metabolism, fat burning, and muscle growth in the lab.Scientists at The Scripps Research Institute (TSRI) have successfully tested a drug, called SR9011,in mice that kickstarts metabolism and results in increased muscle development.Essentially, it's an exercise regime in a pill.

SR9011 alters the metabolic profile of skeletal muscle in a manner similar to the changes observed in animals that are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify its metabolism.

Half of the mice studied showed improved running endurance in terms of both time and distance. What was clearly interesting was that a small, drug-like molecule could increase metabolic rate in skeletal muscle and increase exercise endurance.

1.AICAR: acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown.

2.MK-2866: Medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testosterone Replacement Therapy.
 
4.LGD-4033: Pharmacological profile similar to that of enobosarm, Ostarine,MK-2866.

5.GW1516: For obesity, diabetes, dyslipidemia and cardiovascular disease.

6.Andarine(S4): Partial agonist, intended mainly for treatment of benign prostatic hypertrophy.

7.SR9009: Under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice.

8.SR9011: For obesity, diabetes, dyslipidemia and cardiovascular disease.

9.RAD140: New generation for gaining mass and cutting edges.

10.YK11A: SARM and myostatin inhibitor.

Related Products  

How to order quickly and safely? 

    

 
Packaging









Shipping Method










Company Information
Hubei Shinrezing Pharmaceutical Technology Co.,Ltd.(hereafter shorted as Shinrezing) is located in Wuhan Donghu High-Tech Economic Development Zone and established in 2008 with registered capital is RMB 10 million yuan (about USD 1.5 million ). Its manufacturing base is located in Dawu Industrial Park in Dawu County, Xiaogan City, Hubei Province which is built in 2010 with 25,000 square meters covered area.
 
Shinrezing is a rapid growing enterprise, which integrates the production, R&D, sales and trading of APIs, steroid raw materials, pharmaceutical intermediates, plant extracts, other kinds of organic intermediates etc. Shinrezing is not only a manufacturing company but also a trade company, it also has very good cooperation relationships with some manufacturers qualified with GMP, DMF to meet the different customers' needs from grams to tonnage quantity, which makes Shinrezing to be more flexible and easily to supply highly cost-effective products with high quality and better service to customers.
Shinrezing always stands in high starting, high stand and high quality, and masters strict management for production procedure and quality control. All the products must pass our quality test before being sending to customers. Shinrezing's products have been exported to more than 50 countries and regions all over the world, including United States, Europe, Japan, Korea, Russia, Hong kong, Taiwan and so on, and enjoy a good reputation from domestic and oversea customers
 
Shinrezing's mission is: "Innovative and Pragmatic, Mutual Benefits, Serve the World". Every staff member will keep this in mind all the time, and enforce it at every detail of operation and management of the company. We are always trying our best to offer the best services and the most competitive prices with high quality goods for our customers. All honors belong to the past, Shinrezing people will do their best to develop and produce more perfect product and contribute to the chemical pharmaceutical industries worldwide.

We are confident that Shinrezing will be your best solution.





 
FAQ
Order Guide
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept bank transfer, Western Union or Paypal or  Moneygram

Q6:How long does it take to the goods arrived ?
It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7  Do  you  have  any  reshipment  policy ?  
we have good after-sale service and re-shipment policy if the parcel  lose
Our long association with  our clients has brought great benefits
We always take the upmost care in the packaging of our products 
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible  will seize a small number of packages.
In this circumstance we promise reship free  to establish  long term relationship
 
Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.
 
We have formed a technology and management team that cooperate closely with some  overseas Labs  all speak highly of our safe shipping and goods .
please donot hesitate to contact us.
 

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