Â
Â
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells.
The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5Â (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products.
YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic growth properties ofYK11.
How YK11 Works?
YK11 attaches itself to the AR (androgen receptor), but only inducts methods that lead to the traditional side effects of androgens such as growth of body hair and prostate and enhanced aggression - to a restricted degree.
Most SARMS have quite limited androgenic side effects, but frequently only quite few anabolic effects when likened to testosterone. But, this doesn't occur for YK11 as reported in Biological and Pharmaceutical Bulletin in 2013.
YK11 induces muscle cells to make more follistatin (more than DHT does) -Â a strong myostatin inhibitor. YK11 works through the androgen receptor.With that said, YK11 can be as good as testosterone in terms of muscle strengthening, but minus the detrimental side effects.
Conclusion:
YK11 shows a lot of promise as an apt anabolic SARM. With the muscle growth potential it brings, it's as effective as anabolic steroids and prohormones without the unwanted side effects connected to the latter.
SARM YK-11 is a powerful SARM supplement promoting massive lean muscle gains which is a great benefit for those wanting to have an aesthetic and shredded physique.
Dosages and Suggestion:
Recommended maximum dose YK11 is require dosages of 2.0-5.0mg b.i.d. in males and 0.5mg-2mg b.i.d. in females to achieve optimal effects in humans for the noted indications.
Â
SARM Series | ||
MK2866/Ostarine | Â | 841205-47-8 |
GW501516/GSK-516 | Â | 317318-70-0Â |
MK-677 (Ibutamoren) | Â | 159634-47-6Â |
S-4 (Andarine,GTX-007) | Â | 401900-40-1 |
LGD-4033 | Â | 1165910-22-4 |
SR9009 | Â | 1379686-30-2 |
SR9011 | Â | 1379686-29-9 |
YK-11 | Â | 431579-34-9Â |
RAD140 | Â | 1182367-47-0 |
Biggest concerns from Clients:
1.High Rate Of Customs Clearance:
The packages of items won't contain any hormone information and can be sent out to different areas. At present,the rate customs clearance we send to United states and Europe is 95%. As for Canada, Brazil of quite high buckle close rate area, there are many new ways to get through the customs.Â
2. Authentic Steroid Powder:
A.Many suppliers promise to deliver steroids powder and peptides but which do not meet the quality criteria required. Yijing Pharma is the only reliable solution to your desire for a secure and authentic purchase steroids powder.Â
B.Not only do we sell the best steroid powder and peptides available on the market, but also we follow the courses of our customers support and advice.Â
C.Yijing Pharma depends on customer's feedback to keep improving efficient and satisfying results. Your satisfaction as a customer makes us always happy and keeps our production level high.
Order Guide:
Q1: Have your Product Quality been Approved by Third Party Lab ?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.Â
Q2: How to confirm the product quality before placing orders?
A. We can provide free samples for your test, but you need to pay the shipping cost.Â
Q3. How do you treat quality complaint?
A. First of all, our quality control will reduce the quality problem near to zero. If you are not satisfied with the quality, we will send some free goods as replacement or refund your loss.
Â
Advantage:
1)Sufficient fresh stock,can send to you promptly after you do the payment.
2)Professional and discreet packing could be arranged for customs pass guaranteed.
3)Updated tracking information will be provided every other day.
4)Any questions after receiving the powders,feel free to contact us,could be solved immediately.
Â
NO. | Product Name: | Label: | |
1 | Testoste base | TB | |
2 | Testoste Enanthat | TE | |
3 | Testoste Cypionat | TC | |
4 | Testoste Acetat | TA | |
5 | Testoste Propionat | TP | |
6 | Testoste Decanoat | TD | |
7 | Testoste Phenylpropionat | TPP | |
8 | Testoste Blend / Sustan250 | S250 | |
9 | Testoste Undecanoat / Andri | TU | |
10 | Testoste Isocaproat | TI | |
 | |||
11 | Mestero / Provir | Prov | |
12 | 17a-Methyl-1-testoste | 17MT | |
13 | 4-chlorinedehydro-methyl testoste/Turinab | CH | |
14 | Methyl drostanol / Superdl /Methaste | Sup | |
15 | Fluoxymestero / Halotest | Flou | |
16 | Methyltestoste | MT | |
17 | 4-Chlorotestoste Acetate/Closteb acetat | 4CA | |
18 | Mestanolo | Mest | |
19 | Dehydroepiandrostero | Dhe | |
20 | 7-Keto-dehydroepiandrostero | 7Dhe | |
 | |||
21 | Oxandro / Anav | OA | |
22 | Metandien / Diana | DB | |
23 | Oxymetho / Anadr | Oxy | |
24 | Stanoz / winstr | ST | |
25 | Bolde undecanoat / Equipo | EQ | |
26 | Bolde Acetat | BA | |
27 | Bolde base | BB | |
28 | Bolde Cypionat | BC | |
29 | Bolde Propionat | BP | |
30 | Nandr Decanoat | ND | |
 | |||
31 | Nandr Phenylpropiona | NP | |
32 | Nandr base | NB | |
33 | Nandr Cypionat | NC | |
34 | Nandr Undecylat | NU | |
35 | Trenbo Acetat | TBA | |
36 | Trenbo Enanthat | TBE | |
37 | Trenbo Hexahydrobenzyl carbonate / Parabol | TBH | |
38 | Trenbo Base | TBB | |
39 | Drostanol Propionat / Â Master Propionat | DP | |
40 | Drostanol Enanthat / Master Enanthat | DE | |
 | |||
41 | Methenolo Acetat / Primobo Acetat | MA | |
42 | Methenolo Enanthat / Primobol Enanthat | ME | |
43 | Tamoxif Citrate / Nolvad | Nol | |
44 | Clomiph Citrate / Clom | Clo | |
45 | Letr / Letraz / Fema | Let | |
46 | Anastro / Arimi | Ari | |
47 | Exemest /Aromas | Exe | |
48 | Formest / Lentar | Form | |
49 | Cytomel T3 / Liothyronine sodium | T3 | |
50 | L-Thyroxine/ T4 /Â tetraiodothyronine | T4 | |
 | |||
51 | Sildena / Viag | Sil | |
52 | Tadalaf Citrate / Ciali | Cia | |
53 | Vardena / Fardena / Levit | Var | |
54 | Dapoxeti / Prili | Dap | |
55 | Yohimbine Hydrochloride / Corynine / Aphrodine | Yoh | |
56 | Dutasteri / Avoda | Dut | |
57 | Finasteri / Prosc | Fin |
How to order quickly and safely?Â
Step 1 (Inquiry) | Please let me know the items you are favorable, quantities, and the destination country. |
Step 2 (Offer) | We offer you price and the suitable shipping method for your reference. |
Step 3 (Negotiation) | We will negotiate price, terms of payment, transport, delivery time, arrival time, destination of the goods and after-sales service. |
Step 4 (Order) | After receiving your order, we will check it and get prepared for it. |
Step 5 (Payment) | Please confirm the order and pay money 100% in advance, then send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements. |
Step 6 (Package & Delivery) | Parcel will be arranged within 24 hours upon receipt of your payment. And photos will be offered to tell apart the products. |
Step 7 (Tracking number) | If sent by EMS, the tracking number is availabe within 12 hours. The info will be trackable that day or next day. If sent by HKEMS or other express, the tracking number will be provided next day. And this does not mean the info is trackable that day. It will be released on internet 2 or 3 days later, because the parcel has to be shipped to Hongkong fist, and then wait for the flight. |
Step 8 (After-Sales Service) | Within the terms of the contract, If there is any problem about the goods quality, quantity and other problems, we will assure you to make you satisfied with the results.  |
Our 3Â Guarantes:Â
No. 1: Guality Guaranteed: All our steroids with USP/BP/EP Standard and Purity 98.57%min
No. 2: Shipping Time Guaranteed: We can send out parcel within 12- 24 hours after receiving your payment, and shipping way recommand based on your location.Â
No. 3: Delivery Guaranteed: We guarantee safety shipping, If the parcel is seized/lost/damaged and you receive seizure letter from authority, we will resend the same product for free immediately. We care your business plan and we will never disappoint you.Â
Â
2018 exhibition API and CHPI:
Â
Â
Â
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells.
The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5Â (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products.
YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic growth properties ofYK11.
How YK11 Works?
YK11 attaches itself to the AR (androgen receptor), but only inducts methods that lead to the traditional side effects of androgens such as growth of body hair and prostate and enhanced aggression - to a restricted degree.
Most SARMS have quite limited androgenic side effects, but frequently only quite few anabolic effects when likened to testosterone. But, this doesn't occur for YK11 as reported in Biological and Pharmaceutical Bulletin in 2013.
YK11 induces muscle cells to make more follistatin (more than DHT does) -Â a strong myostatin inhibitor. YK11 works through the androgen receptor.With that said, YK11 can be as good as testosterone in terms of muscle strengthening, but minus the detrimental side effects.
Conclusion:
YK11 shows a lot of promise as an apt anabolic SARM. With the muscle growth potential it brings, it's as effective as anabolic steroids and prohormones without the unwanted side effects connected to the latter.
SARM YK-11 is a powerful SARM supplement promoting massive lean muscle gains which is a great benefit for those wanting to have an aesthetic and shredded physique.
Dosages and Suggestion:
Recommended maximum dose YK11 is require dosages of 2.0-5.0mg b.i.d. in males and 0.5mg-2mg b.i.d. in females to achieve optimal effects in humans for the noted indications.
Â
SARM Series | ||
MK2866/Ostarine | Â | 841205-47-8 |
GW501516/GSK-516 | Â | 317318-70-0Â |
MK-677 (Ibutamoren) | Â | 159634-47-6Â |
S-4 (Andarine,GTX-007) | Â | 401900-40-1 |
LGD-4033 | Â | 1165910-22-4 |
SR9009 | Â | 1379686-30-2 |
SR9011 | Â | 1379686-29-9 |
YK-11 | Â | 431579-34-9Â |
RAD140 | Â | 1182367-47-0 |
Biggest concerns from Clients:
1.High Rate Of Customs Clearance:
The packages of items won't contain any hormone information and can be sent out to different areas. At present,the rate customs clearance we send to United states and Europe is 95%. As for Canada, Brazil of quite high buckle close rate area, there are many new ways to get through the customs.Â
2. Authentic Steroid Powder:
A.Many suppliers promise to deliver steroids powder and peptides but which do not meet the quality criteria required. Yijing Pharma is the only reliable solution to your desire for a secure and authentic purchase steroids powder.Â
B.Not only do we sell the best steroid powder and peptides available on the market, but also we follow the courses of our customers support and advice.Â
C.Yijing Pharma depends on customer's feedback to keep improving efficient and satisfying results. Your satisfaction as a customer makes us always happy and keeps our production level high.
Order Guide:
Q1: Have your Product Quality been Approved by Third Party Lab ?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.Â
Q2: How to confirm the product quality before placing orders?
A. We can provide free samples for your test, but you need to pay the shipping cost.Â
Q3. How do you treat quality complaint?
A. First of all, our quality control will reduce the quality problem near to zero. If you are not satisfied with the quality, we will send some free goods as replacement or refund your loss.
Â
Advantage:
1)Sufficient fresh stock,can send to you promptly after you do the payment.
2)Professional and discreet packing could be arranged for customs pass guaranteed.
3)Updated tracking information will be provided every other day.
4)Any questions after receiving the powders,feel free to contact us,could be solved immediately.
Â
NO. | Product Name: | Label: | |
1 | Testoste base | TB | |
2 | Testoste Enanthat | TE | |
3 | Testoste Cypionat | TC | |
4 | Testoste Acetat | TA | |
5 | Testoste Propionat | TP | |
6 | Testoste Decanoat | TD | |
7 | Testoste Phenylpropionat | TPP | |
8 | Testoste Blend / Sustan250 | S250 | |
9 | Testoste Undecanoat / Andri | TU | |
10 | Testoste Isocaproat | TI | |
 | |||
11 | Mestero / Provir | Prov | |
12 | 17a-Methyl-1-testoste | 17MT | |
13 | 4-chlorinedehydro-methyl testoste/Turinab | CH | |
14 | Methyl drostanol / Superdl /Methaste | Sup | |
15 | Fluoxymestero / Halotest | Flou | |
16 | Methyltestoste | MT | |
17 | 4-Chlorotestoste Acetate/Closteb acetat | 4CA | |
18 | Mestanolo | Mest | |
19 | Dehydroepiandrostero | Dhe | |
20 | 7-Keto-dehydroepiandrostero | 7Dhe | |
 | |||
21 | Oxandro / Anav | OA | |
22 | Metandien / Diana | DB | |
23 | Oxymetho / Anadr | Oxy | |
24 | Stanoz / winstr | ST | |
25 | Bolde undecanoat / Equipo | EQ | |
26 | Bolde Acetat | BA | |
27 | Bolde base | BB | |
28 | Bolde Cypionat | BC | |
29 | Bolde Propionat | BP | |
30 | Nandr Decanoat | ND | |
 | |||
31 | Nandr Phenylpropiona | NP | |
32 | Nandr base | NB | |
33 | Nandr Cypionat | NC | |
34 | Nandr Undecylat | NU | |
35 | Trenbo Acetat | TBA | |
36 | Trenbo Enanthat | TBE | |
37 | Trenbo Hexahydrobenzyl carbonate / Parabol | TBH | |
38 | Trenbo Base | TBB | |
39 | Drostanol Propionat / Â Master Propionat | DP | |
40 | Drostanol Enanthat / Master Enanthat | DE | |
 | |||
41 | Methenolo Acetat / Primobo Acetat | MA | |
42 | Methenolo Enanthat / Primobol Enanthat | ME | |
43 | Tamoxif Citrate / Nolvad | Nol | |
44 | Clomiph Citrate / Clom | Clo | |
45 | Letr / Letraz / Fema | Let | |
46 | Anastro / Arimi | Ari | |
47 | Exemest /Aromas | Exe | |
48 | Formest / Lentar | Form | |
49 | Cytomel T3 / Liothyronine sodium | T3 | |
50 | L-Thyroxine/ T4 /Â tetraiodothyronine | T4 | |
 | |||
51 | Sildena / Viag | Sil | |
52 | Tadalaf Citrate / Ciali | Cia | |
53 | Vardena / Fardena / Levit | Var | |
54 | Dapoxeti / Prili | Dap | |
55 | Yohimbine Hydrochloride / Corynine / Aphrodine | Yoh | |
56 | Dutasteri / Avoda | Dut | |
57 | Finasteri / Prosc | Fin |
How to order quickly and safely?Â
Step 1 (Inquiry) | Please let me know the items you are favorable, quantities, and the destination country. |
Step 2 (Offer) | We offer you price and the suitable shipping method for your reference. |
Step 3 (Negotiation) | We will negotiate price, terms of payment, transport, delivery time, arrival time, destination of the goods and after-sales service. |
Step 4 (Order) | After receiving your order, we will check it and get prepared for it. |
Step 5 (Payment) | Please confirm the order and pay money 100% in advance, then send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements. |
Step 6 (Package & Delivery) | Parcel will be arranged within 24 hours upon receipt of your payment. And photos will be offered to tell apart the products. |
Step 7 (Tracking number) | If sent by EMS, the tracking number is availabe within 12 hours. The info will be trackable that day or next day. If sent by HKEMS or other express, the tracking number will be provided next day. And this does not mean the info is trackable that day. It will be released on internet 2 or 3 days later, because the parcel has to be shipped to Hongkong fist, and then wait for the flight. |
Step 8 (After-Sales Service) | Within the terms of the contract, If there is any problem about the goods quality, quantity and other problems, we will assure you to make you satisfied with the results.  |
Our 3Â Guarantes:Â
No. 1: Guality Guaranteed: All our steroids with USP/BP/EP Standard and Purity 98.57%min
No. 2: Shipping Time Guaranteed: We can send out parcel within 12- 24 hours after receiving your payment, and shipping way recommand based on your location.Â
No. 3: Delivery Guaranteed: We guarantee safety shipping, If the parcel is seized/lost/damaged and you receive seizure letter from authority, we will resend the same product for free immediately. We care your business plan and we will never disappoint you.Â
Â
2018 exhibition API and CHPI:
Â
Herbal Medicine,Herbal Medicine San Diego,Herbal Medicine Degree,Herbal Medicine Books
Fruit-Vegetable Powder, Herbal Medicine Co., Ltd. , http://www.nbplantextract.com