Caffeine may complicate the diagnosis and treatment of hypertension
September 06, 2016 Source: Noble
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Coffee is widely welcomed by people all over the world. In the United States, more than 50% of people drink coffee and spend up to $40 billion a year on this drink.
Studies have shown that caffeinated coffee causes a rapid increase in blood pressure, while caffeine-free coffee does not. Caffeine appears to be a major factor influencing blood pressure, so experts suggest that it can also trigger cardiovascular events.
However, people who regularly drink coffee and caffeine do not face such risks because they are already tolerated. This shows that the time interval between people drinking coffee has a certain meaning.
However, for people who occasionally drink coffee instead of drinking regularly, the situation may be completely different.
How does coffee affect blood pressure test results?
A research team from Ontario, Canada, the Lawson Institute of Health in London and Western Universities, in the process of testing the effects of occasional coffee on blood pressure, especially how coffee intake affects the effects of calcium channel blockers Some unexpected results were found.
Calcium channel blockers are a blood pressure lowering drug. They are usually prescribed for patients with hypertension. Calcium channel blockers such as felodipine are able to relax blood vessels and make blood flow smoother. In this way, lower blood pressure.
The research team led by Dr. David Bailey, a scientist and researcher from the Western University School of Medicine and Dentistry and the Lawson Health Institute, wanted to see if a person quits caffeine long enough to eliminate the effects of caffeine on his blood pressure. What happened.
What they want to see is that the next time the person drinks coffee, the blood pressure will rise, because drinking coffee after quitting caffeine will offset the antihypertensive effect of felodipine.
Quit coffee after a period of time, causing blood pressure to rise
To test their theory, they invited 13 people with an average age of 52 years and normal blood pressure to participate in the experiment.
They tested the subjects three times at intervals of one week. Before each test, they did not drink coffee, did not eat caffeinated food or other substances such as alcohol, grapefruit, oranges, tobacco, etc., and did not take the drug within 48 hours.
After a week, the participants did the following steps and then measured the blood pressure:
Drink two cups of 300 ml of black coffee first.
Take the maximum recommended dose of felodipine extended release tablets (10 mg)
Coffee plus a dose of felodipine.
The results showed that participants only quit coffee for only 2 days, and caffeine was completely eliminated from the body, causing them to raise their blood pressure after drinking coffee again.
Just drinking a cup of coffee, the participants in the coffee group only had the highest blood pressure. Blood pressure began to rise within an hour after drinking coffee and lasted for several hours.
Coffee combined with felodipine is more likely to cause elevated blood pressure levels than taking felodipine alone. This may be because caffeine hinders the positive effects of drugs on blood vessels, the researchers said.
They pointed out that a cup of coffee in the morning may affect the diagnosis and treatment of high blood pressure.
“Even if a cup of coffee contains relatively little caffeine, it will significantly reduce the antihypertensive effect of the drug's maximum recommended dose. If you want to overcome this effect of coffee, you must have this antihypertensive drug. The dose is doubled, and this may increase the risk of side effects that may be caused by overdose, especially during periods when not drinking coffee,†Dr. David Bailey said.
Dr. Bailey is concerned that if a patient visits their doctor after drinking coffee, it will complicate the diagnosis and treatment of high blood pressure. A sharp rise in blood pressure may lead to over-prescription of antihypertensive drugs.
He pointed out that 15-20% of people only occasionally drink coffee. People who drink coffee twice or less a week may have an occasional increase in blood pressure. Some people have higher levels of blood pressure than others.
Dr. Bailey pointed out that national and international guidelines on hypertension did not take into account the effects of coffee because of the lack of evidence.
He hopes that further research will provide more data, and that people who occasionally drink coffee can be more aware of the risks they face.
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