Release date: 2016-04-26
The Boston Children's Hospital, the number one in the United States, developed a Feverprints APP to determine fever symptoms based on researchkit. Unlike some other ResearchKit studies, Feverprints is open to the public in the form of crowdsourcing. Feverprints collects information on fever temperature, symptoms, and diseases of different populations through the App, evaluates normal body temperature changes under the influence of different factors such as one day, and judges the diagnosis of different diseases based on different types of fever, and evaluates different fever suppressing drugs. Symptom control and effects in the disease process.
Dialogue guest: Jared B. Hawkins, MD, Ph.D., Ph.D., Boston Children's Hospital, Computational Medical Informatics Program, Director of Innovation and Digital Medical Accelerator; Harvard Medical School Pediatric Lecturer; Ruiren Medical Technology (hereafter referred to as Ruiren Medical) Analysis consultant.
The reporter had the privilege of having a conversation with Dr. Jared B. Hawkins, one of the project leaders. The following is the interview:
What was the original purpose of the Feverprints app developed by Boston Children's Hospital? What problems should I solve?
Jared: At Boston Children's Hospital, we started researching fever in 2014, and fever has been with human disease for thousands of years. However, it is worth noting that we do not know what normal body temperature looks like. The standard concept is that the normal body temperature is around 37 ° C and the body temperature is over 38 ° C, but these are based on research hundreds of years ago.
In 2015, Ruiren Medical Technology Co., Ltd. reached a cooperation with us to officially bring the Thermia project into China, and jointly developed intelligent hardware and APP based on Thermia fever management technology framework. This intelligent hardware is the wearable thermometer “Fever Directorâ€. The name "iThermonitor". This powerful tool supports our development. It provides valuable information and routine treatment options to parents who are concerned about children with fever and related symptoms, such as the dose of the drug. In the cooperation, we realized that the huge application potential of continuous temperature data will enable us to better understand the body temperature of normal people and patients.
The development of Feverprints has three main intents:
First, it aims to use modern technology, including smartphones and continuous temperature monitoring, to re-examine historical research and collect the body temperature of thousands of people across the United States to unravel what is the normal body temperature;
Second, it seeks to confirm the theory that the fever type of fever is useful for the diagnosis of many diseases;
Third, it is intended to show whether the use of antipyretics actually improves or worsens the progression of the disease. Temperature data at any interval will help in the study, and of course, the continuous data obtained from wearable devices is probably the most abundant.
How does Feverprints guide patients to treatment?
Jared: The three goals of the Feverprints project will affect medical solutions.
First, a better understanding of "normal" body temperature and differences between individuals can allow us to establish a normal baseline for a person's body temperature. From this baseline, monitoring significant changes in patients may provide useful information about health;
Second, prima facie evidence suggests that at least some diseases (eg, periodic fever, aphthous stomatitis, pharyngitis, cervical lymphadenitis syndrome, PFAPA), fever fever may have unique symptoms. We hope that we can capture these unique fever maps and use this information to help with medical diagnosis;
Finally, we found that taking antipyretics found that different diseases were taken? Drugs may improve the disease and may worsen the disease. We hope that our findings can directly guide the treatment of such cases. While all data is useful for our analysis, continuous body temperature data has the greatest potential to bring important findings. At present, we are exploring and providing a number of free continuous monitoring devices to some project participants.
What achievements has Feverprints achieved so far? How many daily users do you have?
Jared: Feverprints was born only 2 weeks, and we are very pleased that many active users have downloaded the software. The number is still growing, and we plan to update this app in the future to add more features.
Apple said that they will launch the CareKit open source platform in April. Will Feverpints use this opportunity to develop patient-oriented apps?
Jared: At Boston Children's Hospital, we are studying the use of CareKit to improve the ability to care for patients. Future versions of Feverprints may take advantage of this framework, but at least for now, we are more concerned with data collection and analysis of the current version.
In addition to the iPhone and Apple Watch, will Feverpints work with other wearable devices?
Jared: Feverpints is an iOS app designed for Apple phones and iPod touch. People can read temperature data through HealthKit - any device that supports HealthKit software (for example, the director of fever of Ruiren Medical). Currently, we are not planning to support Apple Watch or other systems.
How does Feverpints ensure efficient data collection?
Jared: Feverpints receives data in two ways. First, body temperature, symptoms, medications, and survey data that can be directly entered into the APP. Second, body temperature data can be read directly from HealthKit, which now supports HealthKit (for example, Ruiren Medical's fever director).
What efforts did Feverpints do to protect personal privacy?
Jared: On the back end, we used the open source software C3-PRO (also developed at Boston Children's Hospital) to link our anonymous data from the ResearchKit APP (hosted by Amazon Web Services) to the hospital on a large scale and securely. On the server. Although the user's data is completely anonymous, we follow the Boston Children's Hospital's protocol standards to ensure data security.
Does Feverpints have plans to explore overseas audiences?
Jared: Currently, the ethical review we have adopted is to collect data for the US. However, in the future we plan to expand research in other countries.
How does Feverprints work with Boston Children's Hospital or take advantage of Boston Children's Hospital resources?
Jared: Feverprints is a collaboration between the Boston Children's Hospital's Innovation and Digital Medical Accelerator and the Center for Spontaneous Inflammatory Diseases. All development was done in the courtyard of the Boston Hospital. In addition, we used the open source software C3-PRO (also developed at Boston Children's Hospital) to connect our anonymous data from ResearchKit APP (hosted by Amazon Web Services) to hospital servers on a large scale and securely.
What actions and cooperation does Boston Children's Hospital take in digital health?
Jared: Boston Children's Hospital is a leader in digital healthcare for individuals and groups. Our computational medical informatics program has developed some of the most prominent public health surveillance systems of the 21st century. The computational epidemiology group led by Dr. John Brownstein designed healthmap.org, flunearyou.org, vaccinefinder.org and medwatcher.org. These systems assist online data and provide real-time information for public health emergencies; these systems are also used by governments and international organizations (Centers for Disease Control and Prevention, US Department of Health and Human Services, Department of Defense, and World Health Organization).
We are also actively building other tools that provide a basis for health decision-making to educate the public. Thermia provides valuable information and routine treatment options (including drug dosages) to parents who are concerned about children with fever and related symptoms. Thermia's API is already available for Ruiren Medical, and can also be accessed through the app of the fever director's smart thermometer. Our innovation and digital medical accelerators are developed and deployed by our own clinicians (and in some cases external partners) to support the needs of our hospitals and other hospitals.
In addition, at Boston Children's Hospital, we are further expanding the work of feverprints. Currently, we are preparing to provide some active users with some free fever director equipment. I hope this will motivate users to continue to participate and provide richer data analysis. We will also study the feasibility of Feverprints' landing in China, which will increase our sample size and provide us with more research data. We are looking forward to the future of feverprints.
Source: Arterial Network
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