Man-made fibers can "clean up" blood uremic toxins

Release date: 2014-02-25

The Japanese research team mixed zeolites capable of adsorbing creatinine into the resin to make a very fine fiber and made the fiber into a nonwoven fabric. Serum experiments have shown that as long as about 16 grams of fiber, the creatinine produced by a person weighing 60 kilograms within 1 hour can be completely absorbed. The Japanese Institute of Materials and Materials recently published a communiqué saying that its researchers have developed a man-made fiber that can absorb the uremic toxin creatinine contained in the blood of patients with renal failure. This result will help develop portable small-scale dialysis devices. . The research team led by the research director of the agency, Sugawara Hiroshi, mixed the creatinine-adsorbing zeolite into the resin to make a very fine fiber and made the fiber into a non-woven fabric. Serum experiments have shown that as long as about 16 grams of fiber, the creatinine produced by a person weighing 60 kilograms within 1 hour can be completely absorbed. Creatinine is a low molecular uremic toxin in the blood that is formed by the breakdown of creatine and is a major indicator of renal function. When the kidney functiones normally, creatinine is excreted into the body through the urine, but the kidneys of patients with renal failure cannot filter out the metabolic waste and uremic toxins in the blood, so dialysis must be performed. In addition to creatinine, there are many types of uremic toxins. The team believes that by replacing the type of zeolite, man-made fibers that adsorb other uremic toxins can be made. The paper on this achievement has been published in the new issue of Biomaterials Science. At present, there are more than 300,000 patients with chronic renal failure who are receiving dialysis treatment in Japan, which costs about 20 billion US dollars per year. The dialysis device is large and requires a lot of water and electricity, causing a lot of inconvenience to the patient.


Source: China Science and Technology Network

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