Release date: 2014-07-17
Antimalarial drug - artesunate
Scientists and students at the Oregon State University School of Science and Engineering have designed a new type of chemical test that is low-cost, simple to operate, and can determine whether a drug can actually be used to treat malaria, and is expected to help developing countries solve this problem. Deadly problem.
The World Health Organization estimates that about 200,000 people may lose their lives each year by using counterfeit anti-malarial drugs. This new technology from Oregon State University can solve this problem by pre-determining the authenticity of the drug at a cost of just a few cents. If the technology is widely used, it can save thousands of lives around the world, and similar technologies can be used to diagnose drugs for other diseases.
Although the test looks simple and even as cheap as a piece of paper, it is actually a highly complex colorimetric assay. Consumers can use the test to determine if they should take the artesunate they bought – the most important drug for treating severe malaria.
Researchers have found that in some parts of the developing world, 80% of outlets sell counterfeit drugs. A survey showed that 38-53% of outlets in Cambodia, Laos, Myanmar, Thailand and Vietnam are selling inactive drugs. Artesunate is considered an expensive drug in developing countries and costs $1-2 per person for treatment. Since the onset of malaria, it has become a common phenomenon to profit from the sale of counterfeit drugs. In addition to causing thousands of unnecessary deaths, the spread of counterfeit drugs has also contributed to the formation of new multi-drug resistant strains of malaria, causing global safety risks.
This new technology is an application of microfluidics that can detect the presence and level of artesunate drugs. After the tablet is crushed, it is dissolved in water, and a drop is placed on the paper. If yellow appears, the drug is present, and the color depth indicates the level of the drug contained. Undergraduate and graduate students in the Department of Chemistry and Computer Science at Oregon State University are further developing an iPhone app to measure the depth of color and accurately determine the presence and level of the drug. Scientists say the technology is similar to the combination of computers and expensive experimental equipment, simple to operate, and inexpensive, and may be widely used in the medical field.
Source: biodiscover
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