How to detect lymphoma has always been a problem in the pathology world. Pathologists now need to use a variety of complicated methods to detect. Even so, the process of detection is still as difficult as finding a needle in a haystack. Recently, however, scientists at the University of Missouri in the United States have developed a new sound and light technology that uses laser pulses to scan lymphoma. The principle of this technique is to use the characteristics of malignant melanoma in lymphoma that easily react with laser pulses. They absorb the pulse and the volume expands and shrinks rapidly due to temperature changes. In the process of expansion/contraction, the shock wave is sent outwards, so scientists can use special sensors to collect these shock waves, so that they can be accurately and quickly Determine if the patient has lymphoma and a specific part of the disease.
According to John Viator, a member of the research team: "It's like a stuffed cake. In order to find out where the stuffing in the cake is, the way we take it is not to directly look at the cake, but to use the ultrasound probe at the most likely The part of the filling is scanned, and if a signal is detected, it means that there is stuffing in this part. This method greatly saves the time and cost of the doctor to check lymphoma."
In July 2009, Viator published an article in the journal Biomedical Engineering entitled "Sound and Light Detection Methods for Malignant Melanoma in Sentinel Lymph Nodes". He is currently working with Professor Jae Kwon of the University of Missouri. Related research. The research team is currently studying how to use gold nanoparticles to detect cancer cells without melanin, so that this sound and light detection technology can be applied to the detection of other cancer cells such as breast cancer cells.
"Malignant melanoma of lymphoma contains melanin, while breast cancer cells do not contain any pigment, so we generally can't use lasers to illuminate these cells to react. But we are currently studying a colorless Cancer cells are stained with nanomaterials so that our detection methods can be extended to the detection of various cancers."
Viator also said he hopes the test method will be commercialized as soon as possible, and that the test tool "is a powerful tool for humans to fight cancer." In addition, the research team's latest research on this method of sound and light detection will be published in the journal Biomedical Engineering in the coming months.
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